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Aardvark Therapeutics, Inc. (AARD) Cantor Fitzgerald Global Healthcare 2025 Transcript

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Aardvark Therapeutics, Inc. (NASDAQ:AARD) Cantor Fitzgerald Global Healthcare Conference 2025 September 3, 2025 11:30 AM EDT

Company Participants

Tien-Li Lee – CEO, Secretary & Director

Conference Call Participants

Joshua Schimmer – Cantor Fitzgerald & Co., Research Division

Presentation

Joshua Schimmer
Biotech Equity Research Analyst

All right. I think we’re ready to get started with our next session. I’m Josh Schimmer from the Cantor Biotech Equity Research team. Very pleased to introduce from Aardvark Therapeutics, Tien Lee, Chief Executive Officer and Founder. Tien, give us a quick snapshot of Aardvark, and we’ll then dive into all things, TAS2R agonists.

Tien-Li Lee
CEO, Secretary & Director

Okay. Great. Yes.

Joshua Schimmer
Biotech Equity Research Analyst

And by the way, Tien’s birthday is today. No better way than to celebrate with us, right?

Tien-Li Lee
CEO, Secretary & Director

Thank you. Thank you, Josh. Appreciate it. Yes. So Aardvark is a San Diego-based biotech company. We’re focused on small molecule drug development. We have a unique category of drugs. It’s a gut-brain signaling drug. It’s small molecule oral, but it’s gut restricted and it mostly stays in your gut, but it’s signaling gut-brain pathway to mediate a bunch of things, including abrogating hunger.

Question-and-Answer Session

Joshua Schimmer
Cantor Fitzgerald & Co., Research Division

And maybe talk a little bit about that pathway, right? So you consume something bitter, now its taste mess, you don’t taste it. And yet it gets into the stomach. What’s it signaling? What are kind of these upstream effects that ultimately impact appetite?

Tien-Li Lee
CEO, Secretary & Director

Sure, sure. First off, it’s counterintuitive, but you have taste receptors in your gut, not just your mouth. And as you mentioned, we bypass the oral cavity, so you don’t want to taste our drug in your mouth. And it’s hitting enteroendocrine cells, which are the cells that help regulate eating behavior. And

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